Selected Publications
Selected High-Impact Publications
My publication portfolio reflects interdisciplinary leadership across genomics, infectious disease, immune profiling, and translational diagnostics. The work below highlights contributions in high-impact journals spanning molecular biology, computational immunology, and clinical infectious disease.
Precision Infectious Disease Diagnostics & Immune Profiling
Disease diagnostics using machine learning of B cell and T cell receptor sequences
Science
Contributed to computational frameworks leveraging adaptive immune receptor sequencing for disease classification and diagnostic inference. This work positioned immune repertoire analytics as a scalable platform for precision diagnostics, integrating machine learning with translational immunology.
Phage diversity in cell-free DNA identifies bacterial pathogens in human sepsis cases
Nature Microbiology
Contributed to integrative analysis linking circulating phage signatures in cell-free DNA to pathogen identification in sepsis. This work established a novel host–pathogen detection framework with direct implications for non-invasive infectious disease diagnostics.
Clinical Virology & Disease Trajectory Modeling
SARS-CoV-2 RNAemia predicts clinical deterioration and extrapulmonary complications from COVID-19
Clinical Infectious Diseases
Integrated molecular viral load measurements with clinical outcome data to define RNAemia as a predictor of disease severity. Bridged virology and translational risk stratification frameworks.
Re-visiting humoral constitutive antibacterial heterogeneity in bloodstream infections
The Lancet Infectious Diseases
Characterized immune heterogeneity in systemic infections through integrative host-response analysis. Provided insights relevant to precision infectious disease management.
Molecular & Systems Microbiology
Neutrophil extracellular traps have active DNAzymes that promote bactericidal activity
Nucleic Acids Research
Co-developed mechanistic insights into DNAzyme activity within neutrophil extracellular traps, redefining functional understanding of innate immune bactericidal mechanisms.
The Transcriptional landscape of Streptococcus pneumoniae TIGR4 reveals complex operon architecture and riboregulation
PLoS Pathogens
Directed comprehensive transcriptomic mapping in a clinically relevant bacterial pathogen, defining regulatory networks critical for virulence and growth.